The final design I came up with put the ships in two batches. Batch One would be designed for littoral warfare - ISR, naval gunfire support, SOF support, and some amount of self defense, ASW and ASuW power. I imagine these ships would be the cheaper of the two batches, and take over a lot of the jobs we currently see destroyers and cruisers doing - anti-piracy patrols, showing the flag, and multinational training.
The second batch is more of a blue-water frigate, with more VLS, a 76mm, vice 5" gun, and adapted for ASW and OASuW. These frigates would be the escorts, the pickets and the ASW screens for more valuable ships.